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Hempseed oil derived from *Cannabis sativa* – biochemical composition, health benefits, and practical guidelines for use

Emilia Szymańska

Emilia Szymańska

2026-03-18
4 min. read
Hempseed oil derived from *Cannabis sativa* – biochemical composition, health benefits, and practical guidelines for use
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The annual plant known scientifically as Cannabis sativa variety sativa demonstrates remarkable adaptability to diverse environmental conditions. Its seeds are distinguished by a rich nutritional profile: comprising 15 to 20 percent high-quality plant-based protein and 28 to 35 percent fat—primarily polyunsaturated fatty acids from the omega-3 and omega-6 families, which are deemed essential in human nutrition. Additionally, the seeds’ chemical composition includes a range of bioactive compounds, such as edestin—a highly digestible storage protein—choline, which supports metabolic functions, lecithin as a cellular membrane component, chlorophyll with detoxifying properties, vitamin K critical for blood coagulation, and tocopherols exhibiting antioxidant activity. These unique characteristics position hempseed oil as a valuable asset in both dietary applications and health-promoting strategies [1, 2].

Hemp oil

Hemp oil is a liquid, yellowish-orange, slightly bitter, root-nut-scented and flavoured. It is mainly composed of unsaturated fatty acids (about..90%). The most important are linoleic acid (LA, 4658%), α-linolenic acid (ALA, 1228%) and γ-linolenolic acid (GLA), which belong to the multivariate saturated fatty acid family. Additionally, the oil contains 60110 mg/100 g, carotenoids 3, 112 mg/100g, phytosterols 390670 g/100g and polyphenols 58, 8106, 3/100 g. The average omega-3 to omega-6 levels are available on the internet.

Hemp oil properties

Due to the very high proportion of essential, unsaturated fatty acids, the oil contributes to the production of prostaglandins, which, among others, play a role in the body's response to inflammation. The omega-3 fatty acid content is anti-inflammatory, anti-aggregating and hypotensive, reduces the synthesis of fatty and triglyceride fatty Acids and anti-oxidizes them. The appropriate proportions of omega-6 to omega-3 (3:1) help to counteract inflammatory conditions.

Use of hemp oil

Because of its beneficial fatty acid composition, hemp oil is particularly recommended for people who have chronic inflammatory conditions in the body. It may also be used in cardiovascular diseases. In particular, in coronary heart disease and hypertension and atherosclerosis. Also, the presence of phytosterols may help to restore the balance in the heart and blood vessels. Reducing LDL fraction levels in the raw blood also improves the blood lipid profile.

Hemp oil on your face

Deficiency of fatty acids such as linoleic acid and α-linolenic acid is associated with a symptom of dry skin. Additionally, with age, the amount of enzymes responsible for converting fatty acid to GLA decreases, which also reduces skin moisture. Disruption of the metabolism of essential unsaturated fats in the skin can contribute to atopic inflammation of the skin or follicles. External supply of LA and ALA affects their use in the regenerative lipid layer of skin.

How to use hemp oil?

Hemp oil after opening should be stored in a refrigerator no longer than stated on the label by the manufacturer. No spoiled, coated oil should be used. Hemp Oil can be used both internally and externally. Instead of traditional salad or dessert oils, it can be added cold. When applied to the skin, apply the oil to the waffle and gently wipe the face before applying.
Emilia Szymańska

Emilia Szymańska

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