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Vitamin B6 for Your Well-being!

Felix Weber
Felix Weber ✓
Diets Premium Expert • 25.03.2026
✓
Scientifically reviewed by a clinical dietitian: This article has been peer-reviewed for adherence to IŻŻ, WHO, and PTGiP clinical nutritional standards.
Diets Premium Expert Felix Weber min read 4 min Scientifically reviewed by a clinical dietitian 25.03.2026
Vitamin B6 for Your Well-being!

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Key Takeaways
This article is dedicated to Vitamin B6 and its significance for our body. In 1930, scientists Chick and Copping described a new vitamin, which was named factor I. Four years later, György did the same. In 1935, Birch, György and Harris proved that a deficiency of this vitamin causes acute skin inflammation in rats. The term Vitamin B6 encompasses a group of natural pyridine compounds that undergo mutual transformations in the body and exhibit similar biological effects. Does this have any significance for the human body at all?
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The function and significance of Vitamin B6

Vitamin B6 is water-soluble and absorbed through the digestive tract, primarily stored in muscles and liver as pyridoxal phosphate. It has a significant impact on the nervous system. As a coenzyme, it is involved in the synthesis of glycogen, which serves as a reserve for many important organs, and in the metabolism of complex carbohydrates. It ensures an appropriate level of glycogen production and its conversion into glucose in the body. It is also an excellent protective agent against the development of atherosclerosis and improves the functioning of the circulatory system. Vitamin B6 participates in reactions responsible for the conversion (elongation) of fatty acids. One of the key reactions is the conversion of linoleic acid into arachidonic acid, which is essential for the synthesis of prostaglandins, substances that perform important functions in the body. Furthermore, pyridoxine is necessary for the production of hemoglobin (red blood pigment) and influences blood pressure, muscle contractions, and heart function. It ensures proper functioning of the nervous system and increases the body's resistance, as it is involved in the formation of antibodies.

Consequences of vitamin B6 deficiency and excess

Symptoms of vitamin B6 deficiency are varied and depend on the severity of the deficiency. Possible symptoms include inflammation of the skin, greasy changes in the face, irritation of the tongue and mucous membranes of the oral cavity. There may also be changes to the central nervous system - most commonly apathy, insomnia, hypersensitivity and seizures. A deficiency of vitamin B6 may also increase the risk of infections due to decreased immunity. Anemia may also occur. Furthermore, a deficiency of vitamin B6 may increase the risk of developing cancer. However, vitamin B6 deficiency is rare. Nevertheless, low levels of vitamin B6 can also have negative effects on the health and development of children. Mental developmental delays and bone malformations are among the most serious consequences. Epilepsy-like symptoms, irritability and crying in infants may also occur. The main causes of vitamin B6 deficiency include an unbalanced diet, use of contraceptive pills and use of medication for tuberculosis. An excess of vitamin B6 can also occur as a result of long-term intake of tablets in a dose of more than 200 mg per day. It is important to remember this if someone wants to take these vitamin supplements regularly - an excess of this vitamin supplement can have irreversible effects on our health.

The Sources of Vitamin B6

Buckwheat groats are one of the most abundant sources of vitamin B6. Certain vegetables also serve as excellent sources of this vitamin, such as red bell peppers, potatoes, and leafy greens, which are known for their high content. It is also present in brewer's yeast and whole-grain products like brown rice or wheat bran. Other good sources of vitamin B6 include walnuts, Italian walnuts, legume seeds, and wheat sprouts. Vitamin B6 is also found in meat and animal products, with eggs being particularly recommended. The typical daily requirement for vitamin B6 in humans is 2-3 mg, but factors such as stress, menstruation, pregnancy, heart failure, advanced age, low blood sugar, or the use of contraceptive pills can significantly increase the need for pyridoxine.
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