The hidden risks of excessive folic acid supplementation in women: clinical implications and emerging evidence from scientific research
Felix Weber
2026-03-18
2 min. read
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Recent investigations led by researchers at Canada’s St. Michael’s Hospital have uncovered that prolonged consumption of excessively high doses of folic acid—whether through dietary supplements or fortified foods—may be associated with adverse health outcomes, including the potential acceleration of breast tumor progression. These findings carry significant weight given the widespread recommendations for folic acid supplementation among women planning pregnancy or currently pregnant, where its well-documented role in preventing neural tube defects must now be balanced against the emerging risks of overconsumption.
Folic acid has its ups and downs
Folic acid has many positive properties without which it is difficult for a healthy body. It is especially recommended for pregnant women but also for men. However, folic acid should also be taken into consideration. As scientists at St. Michael's Hospital in Canada show, its excess can have quite different effects. Folic acids found in broccoli, spinach, or Brussels are recommended for women who are pregnant. But often prescriptions that are even supplemented, because the need for folic acid during pregnancy also increases during the preparation period.