5431. Onpattro : Orphan maintenance assessment report (initial authorisation) 5432. Vyxeos : Orphan maintenance assessment report (initial authorisation) 5433. Symkevi : Orphan maintenance assessment report (initial authorisation) 5434. Takhzyro: Orphan maintenance assessment report (initial authorisation) 5435. Trecondi : Orphan maintenance assessment report (initial authorisation) 5436. Isturisa : Orphan maintenance assessment report (initial authorisation) 5437. Givlaari : Orphan maintenance assessment report (initial authorisation) 5438. Fintepla : Orphan maintenance assessment report (initial authorisation) 5439. Pemazyre : Orphan maintenance assessment report (initial authorisation) 5440. Copiktra : Orphan designation withdrawal assessment report (initial authorisation) 5441. Bylvay : Orphan maintenance assessment report (initial authorisation) 5442. Abecma : Orphan maintenance assessment report (initial authorisation) 5443. Voxzogo : Orphan maintenance assessment report (initial authorisation) 5444. Artesunate Amivas : Orphan maintenance assessment report 5445. Xenpozyme : Orphan maintenance assessment report (initial authorisation) 5446. Pepaxti : Orphan designation withdrawal assessment report (initial authorisation) 5447. Tibsovo : Orphan Maintenance Assessment Report (initial authorisation) 5448. Pombiliti : Orphan Maintenance Assessment Report (initial authorisation) 5449. Elrexfio : Orphan designation withdrawal assessment report (initial authorisation) 5450. Omjjara : Orphan maintenance assessment report (initial authorisation) 5451. Agilus : Orphan designation withdrawal assessment report 5452. Elahere : Orphan maintenance assessment report - initial authorisation 5453. Rytelo : Orphan maintenance assessment report (initial authorisation) 5454. Ezmekly : Orphan maintenance assessment report (initial authorisation) 5455. Tryngolza - Orphan maintenance assessment report (initial authorisation) 5456. Protelos-H-C-560-A20-0034 5457. Voncento-H-C-2493-P46-010.1 5458. Twinrix Paediatric-H-C-129-P45-0042 5459. Mimpara-H-C-570-P46-0028 5460. Synflorix-H-C-973-P46-058