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Semaglutide how it works and how to use it
Table of Contents
1. That's how semaglutide works
GLP-1 is produced mainly in the gut and causes glucose to decrease by increasing insulin secretion through the pancreas. Importantly, under hypoglycaemia, or too low blood glucose, it decreases insulin's release, thereby regulating glycaemia accordingly. GLP-1- can also reduce appetite and thus the amount of food and drink taken. Semaglutide is a compound that mimics the action of the human hormone GLP-1, a glucagon-like peptide.2. This item is intended to serve as a starting point for the preparation of the report
So far, 4 out of 6 clinical trials have been published and their effects on body weight have also been examined.3. It is not possible to calculate the amount of the loan
In both groups, lifestyle-related interventions were also used. They lost an average of 14.9% of their baseline body weight, compared with only 2.4% in the second group. The second group had less than 5% of this effect. They were divided into 2 groups The first group received 2.4 mg of semaglutide per week, the second received placebo. After 68 weeks, the first group had a much better effect. More than half of the participants in the semaglutide group lost 15% or more of their base body weight.4. The Commission shall adopt delegated acts in accordance with the opinion of the Standing Committee on Plants, Animals, Food and Rural Affairs and the Committee on the Environment, Public Health and Consumer Protection
The subjects were divided into 2 groups The first group received 1 mg of semaglutide, the second group received 2.4 mg and the third group received placebo. In the first group the average weight loss was 6.99%. The duration of the intervention was also 68 weeks.5. The Commission shall adopt delegated acts in accordance with the opinion of the Standing Committee on Plants, Animals, Food and Rural Affairs and the Committee on the Environment, Public Health and Consumer Protection
In addition, some people were given semaglutide, some placebo, and in the third study, overweight people with co-existing but non-diabetic conditions were included. After 68 weeks, the average weight loss was 16% in the drug group and 5.7% in the placebo group. Each of the subjects received intense psychological support in implementing appropriate lifestyle changes.6. It is not possible to calculate the value of the goods in the same way as the price of the product
The subjects in the placebo group increased their body weight by an average of less than 7% from 20 weeks to 68 weeks; it is still not known what the long-term effect of the drug will be and at what rate the body weight will increase after stopping the drug. However, the potential side effects are much higher. For the next 48 weeks, some of them continued to take the drug, while others received a placebo.7. Seamaglutide - side effects
It is not known whether the medicine is safe for patients with a history of pancreatic inflammation. it may also increase the risk of developing pancreatitis, gallstones and kidney failure. as with any medicinal product, semaglutid can cause side effects such as nausea, vomiting, diarrhea, constipation, abdominal pain, headache, fatigue, dizziness, hypoglycemia in patients with diabetes, bloating, persistent inflammation of the intestine, reflux. the leaflet also contains information about the increased incidence of cancer in males who take it (the increased risk of cancer has been reported in studies of breast cancer). it also increases the likelihood of developing depression and other disorders.8. Semaglutide contraindications for use
As with any medicinal product, it cannot be used by people with an allergy to the active substance or other ingredients. Although semaglutide can effectively aid weight loss, a balanced diet and physical activity are essential for achieving proper weight gain. Unfortunately, there is no magic pill that can definitively solve the problem of being overweight without effort, but semaglutide is a potential medicine that can greatly facilitate weight loss.
