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Metabolically healthy obesity
Table of Contents
1. The definition of obesity
Obesity is also divided into two types: transverse (ginoidal) and abdominal (androidal) obesity. In most cases, people with a BMI of more than 30 kg/m2 have elevated blood glucose levels, high cholesterol levels, dyslipidemia or hypertension. These cases are classified as metabolically healthy obesity, and a diagnostic criterion is a BMI that must be at least 30kg/m2. From a metabolic point of view, the latter is much more dangerous and can have a number of health consequences.2. Is obesity metabolically healthy at all?
Obese metabolically healthy individuals are considered to be those who do not exhibit insulin resistance, hypertension, fatty tissue obesity and have normal fasting glucose levels, respectively high levels of so-called good cholesterol (HDL) and low levels of triglycerides in the blood (R.L. The most important determinant of metabolic disorders in obese people is insulin fat distribution. Stefan, H.-U. Schulze, 2018). Gummesson, P.E. and colleagues also stated in a 2018 study that high blood glucose (high blood cholesterol) levels and low blood sugar (low blood sugar) levels are a direct contributing factor to lower metabolic risk in the body after a full-blooded metabolism study has been conducted. However, it is widely observed that the effects of obesity in men and women are also significantly reduced (see Figure 2 below, Figure 1).3. Does this even mean that you can be obese and always be healthy?
In fact, people with MHO are less likely to develop type 2 diabetes than obese people with a metabolic syndrome, but the risk is still more than 4 times higher compared to those who are thin (J.A. Kivimaki, M.M. The same is true for women with a risk of developing cardiovascular disease, which is more than 2 times higher than in healthy people (R.C. When it comes to overall mortality, it depends on the number of metabolic disorders that can occur in laboratory studies and are not directly linked to weight loss).4. They're metabolically obese with the right body mass
Researchers disagree on how to diagnose MONW. However, it is known that at least 2 of the criteria must be met: elevated blood pressure, increased fasting glucose, insulin resistance, waist circumference above 80 cm in women and above 94 cm in men, hyperglyceremia or reduced HDL cholesterol fraction or increased fat tissue content (cutting points vary depending on the study) (K. Pupek-Mlik, P. When describing metabolically healthy people, one cannot fail to mention those who are metabolically obese despite their normal body weight (MON).5. Can MONW be treated?
When the waist circumference is too large, consideration should be given to weight reduction. It is also worthwhile to focus on folic acid and vitamin B12 and B6 in the diet to avoid increased homocysteine levels, which may be associated with reduced fertility or the development of cardiovascular disease. An integral factor in the treatment of people with MONW is physical activity tailored to the patient's preferences. When lifestyle changes do not produce the expected effects, pharmacotherapy should be considered, of course, in consultation with a physician (N. Due to the fact that people who do not experience the negative effects of MONW on their diet and diet, and it is very difficult to overcome the effects of obesity, obesity and other metabolic diseases such as type 2 diabetes and obesity are considered to be very beneficial for their lives.
