Is that what leptin is and what does it have to do with obesity?

1. Is that what leptin is and how it works?

2. Leptin resistance and obesity

3. Why doesn't the diet work?

4. Is that what causes leptin resistance and how to prevent it?

5. Summary

1. Is that what leptin is and how it works?

Leptin is a hormone produced almost exclusively by adipocytes. The concentration of leptin circulating in the blood is directly proportional to the amount of fat in the body. Its main functions are to transmit information to the brain about the body's fat resources and to regulate appetite and satiety. It is done by receptors in the subcutaneous tissue. The pattern of action seems simple. The more we eat, the more fat cells are in our body.

2. Leptin resistance and obesity

Obese people have a significant amount of fat in their body that produces a lot of leptin. Given the mechanism of action of the hormone, such people should not overeat, their brain should be informed that there is enough fat. So why not? The problem is that the signal is not being picked up. Although there is a huge amount of leptine circulating in the bloodstream, the brain is unable to read it.

3. Why doesn't the diet work?

People who lose weight very often struggle with weight loss. The effects of weight loss are rarely long-term. There may be many reasons for this phenomenon, but it seems that somehow leptin may also be responsible for it. During rapid, rapid weight loss, hormone levels drop dramatically. This is a signal to the brain that the amount of energy in the body has decreased significantly, so it starts protecting fat tissue using the biochemical forces that make us eat.

4. Is that what causes leptin resistance and how to prevent it?

Studies have identified several biological mechanisms that may be responsible for the formation of leptin resistance. These include inflammatory states, high levels of free fatty acids in the blood, and high leptin levels. As is easy to see, all of these factors are widely recognized as increasing the risk of obesity. A false circle is formed in which obese people become more resistant to leptin, causing even greater buildup of fat. So what can we do to prevent this from happening?

5. Summary

Obesity isn't always caused by laziness and a lack of strong willpower. There are also many strong biological conditions at play, and one of the most important ones is the regulation of hunger and satiety by leptin. But it's important to remember that the way we live and what we eat has a huge impact on our bodies.