Is that what leptin is and what does it have to do with obesity?

1. Is that what leptin is and how it works?

2. Leptin resistance and obesity

3. Why doesn't the diet work?

4. Is that what causes leptin resistance and how to prevent it?

1. Is that what leptin is and how it works?

Its main function is to give information to the brain about the body's fatty tissue resources and to regulate hunger and satiety. The scheme of action seems simple. Large amounts of leptin are produced, which sends signals to the subcutaneous tissue and inhibits the appetite center. Low levels of the hormone are a warning to the body about depleting energy stores, stimulating the hunger center. This system should protect us both from overeating and long-term fasting. What leptin is a hormone produced almost exclusively by the body is called adipocytes. It happens by the receptors that are produced in the body underneath the body.

2. Leptin resistance and obesity

So why isn't this happening? Even though there's a huge amount of leptin circulating in the bloodstream, the brain is unable to read it. This condition is called leptin resistance, and it's referred to as one of the major biological conditions of obesity. Given the mechanism of action of the hormone, these people shouldn't overeat, their brain should be told that there is enough fat. The problem is that the signal is not being picked up. They mistakenly think that the body is starving and activates the processes associated with increasing food intake and minimizing energy expenditure.

3. Why doesn't the diet work?

There are many reasons for this phenomenon, but it suggests that leptin may also be responsible for it at some point. It's a signal to the brain that the amount of energy in the body has decreased significantly, which is why it starts protecting the fat tissue using the biochemical forces that force us to eat. People who lose weight very often struggle with the problem of weight loss. During rapid, abrupt weight loss, hormone levels drop dramatically. Maybe that's why dieting is so difficult for some people. The effects of losing weight are rarely long-term.

4. Is that what causes leptin resistance and how to prevent it?

All of these practices have been shown to be beneficial in reducing chronic inflammation in the body and are key to preventing leptin resistance and even its withdrawal. Studies have identified several biological mechanisms that may be responsible for the risk of obesity. This creates a false circle in which obese people become more resistant to leptin, which leads to an even greater accumulation of fatty tissue products.