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Curcumin has health properties

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Curcumin has health properties

In many countries, turmeric is used as a spice to give food its characteristic orange-yellow color. What health benefits does curcumin exhibit, and is it worth incorporating this compound into your daily diet? Its widespread use is due to its coloring and fragrance properties and wide biological activity.

Table of Contents

1. Turmeric and turmeric general characteristics

It is also important to the human body for mineral components such as calcium, iron, sodium, and potassium due to its poor absorption from the gut and rapid digestion in the liver. It is currently grown mostly in China and India. It was first isolated in 1815, and only in 1910, when Polish chemists established its spatial structure. Hewlings, D.S. Because of its weak absorption of calcium and potash in the gut, the concentration of turmeric in its plasma is often less than 1 μmol. Its availability is increased by adding it to the dietary supplements of the poultry compound cucumber, cucumbers, pipetamine, and other poisonous mushrooms.

2. Curcumin has multi-directional health effects

This bioactive component of curcumin may prevent and assist in the treatment of Alzheimer's, Parkinson's and cardiovascular diseases, as well as improve glycaemic control and lipid metabolism in patients with PCOS and metabolic disorders without significant adverse effects (a dose of 80500 mg/day was used in the study).

3. The antioxidant properties of curcumin

Thus, it prevents oxidative stress responsible for the aging processes of the body and the development of many diseases (including Parkinson's or Alzheimer's disease, multiple sclerosis, lateral paralysis, atherosclerosis). Studies have shown that this compound protected rats from oxidative damage to cell molecules (proteins, lipids, nucleic acids) caused by reactive forms of oxygen (R.R. Luthria 2019; D. Kes 2022).

4. The anti-inflammatory properties of curcumin

Curcumin impairs the activation of NF-kB and decreases the expression of the proteins involved in inflammation. A significant decrease in pro-inflammatory cytokine levels has been observed: cancer anxiety factor (TNF-α), interleukin 1b (IL-1B) and interleukine 6 (IL-6), which has significantly improved liver function and reduced inflammation (D. Keskin 2022).

5. The anticancer properties of curcumin

Curcumin has been shown to affect the functioning of many proteins: transcription factors, growth factors, enzymes, or cytokines, and hence affects the process of carcinogenesis and inflammation. Bashang, S. The process of cancer formation is very complicated, although the main cause of cancer is thought to be disorders in the signaling pathways of healthy cells, which are associated with changes in regulatory proteins. However, more clinical studies in humans are needed to assess whether curcumin may be used to treat cancers (H. Tamma 2020).

6. Curcumin for the treatment of joint degenerative disease (JAD)

Therefore, curcumin appears to be a safe and effective supplement for MS patients. However, more studies should be carried out to accurately estimate the safe and efficacious dose of the supplement (L. The studies compared the effects of non-steroidal anti-inflammatory drugs (NSAIDs) and curcumine extract supplementation (10002000 mg/ day) on reducing pain and joint stiffness in patients with MS. Supplementation is recommended for at least 12 weeks. Zeng and 2021.

7. Curcumin is a summary

Work is underway on ways to increase the bioavailability of curcumin from the supplement, and more well-designed studies on a large scale are needed to assess what dose will be safe for long-term use. Curcumin is a widely studied compound with high biological activity, showing multi-directional health effects on the body.

Source

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Fusar-Poli L. et al., Curcumin for depression: a meta-analysis, „Critical Reviews in Food Science and Nutrition” 2020, 60(15), 2643–2653.
Hatipoglu D., Keskin E., The effect of curcumin on some cytokines, antioxidants and liver function tests in rats induced by Aflatoxin B1, „Heliyon” 2022, 8(7), epub.
Hewlings S.J., Kalman D.S., Curcumin: A Review of Its Effects on Human Health, „Foods” 2017, 6(10), epub.
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Lopresti A.L., Curcumin for neuropsychiatric disorders: a review of in vitro, animal and human studies, „Journal of Psychopharmacology” 2017, 31(3), 287–302.
Terlikowska K., Witkowska A., Terlikowski S., Kurkumina w chemoprewencji raka piersi, „Postępy Higieny i Medycyny Doświadczalnej” 2014, 68, 571–578.
Zeng L. et al., The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis, „Bioscience Reports” 2021, 41(6), epub.